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Elm Street Ventures
Elm Street Ventures is a seed and early stage venture fund based in New Haven, Connecticut. Our emphasis is on the life sciences, with approximately 70% of our investments to date in companies developing laboratory tools, diagnostics, medical devices, therapeutics, and other health care related products and services. The remaining 30% of our commitments are in green technology, information technology and other industries.

We believe strongly that successful businesses address an attractive market with products or services well-protected by patents, trade secrets, or other means, an experienced management team, and one or more entrepreneurial founders passionate about building a successful business. An important part of our efforts is focused on creating and initially operating life sciences companies founded on intellectual property developed at Yale University and other research institutions in the region (from New York City through Southern New England).

By providing management expertise and early stage capital, ESV catalyzes new company formation, working closely with scientists, engineers, and entrepreneurs to build significant tec5hnology companies from the seed and early stage.To date, Elm Street Ventures has co-founded and/or provided initial seed financing to nine of the dozen companies in our portfolio.

While we expect to be co-founders of companies in some circumstances, we are also interested in hearing from entrepreneurs, scientists, and engineers who have already formed or plan to form new ventures.

Photo of Adrian Horotan, Elm Street Ventures Adrian Horotan
Elm Street Ventures

Adrian is a Principal of Elm Street Ventures and serves as a board observer on the board of AxioMx, Inc. Prior to joining ESV in 2012, Adrian was a senior associate at Connecticut Innovations. While at CI, Adrian served as a board observer for Solais Lighting, Sustainable Real Estate Solutions, and Thetis Pharmaceuticals. He also worked on CI's investments in HistoRx, Oxford Performance Materials, Biorelix, Queralt, Grey Wall Software, Stone Creek Entertainment, and Precipio Diagnostics. Before CI, Adrian interned with seed venture capital fund Launch Capital and with FE Clean Energy Group.

Adrian also previously worked in corporate finance and strategy in diverse industries including insurance (The Hartford), consumer goods (Diageo Guinness USA), pharmaceuticals (Eli Lilly), and investment banking (ABN AMRO Securities). Adrian holds a Master of Environmental Management degree from the Yale School of Forestry& Environmental Studies, and an MBA from INSEAD (France).

Representative Investments
Desmos, Inc. Desmos, Inc. was founded in 2007 by Yale undergraduates and incubated at the Yale Entrepreneurial Institute until start-up funding was secured. The company develops and markets software that makes technology more useful for teachers and students. Desmos is building a common platform to allow educators to create lesson plans that will work across electronic whiteboards ("smartboards"), tablets (such as iPads), computers, and other devices from multiple manufacturers. The Company provides other software that runs in any browser, offering virtual whiteboard capability for remote, real time collaboration, teaching, and tutoring, and software that permits tutoring companies to manage their resources and client interactions. Desmos offers additional browser based software, such as a graphing calculator.
P2 Sciences, Inc. P2 Sciences, Inc. is developing technology to convert vegetable oils and other renewable feedstocks into specialty chemicals, initially targeting the flavors and fragrances, polymers, lubricants, and surfactants markets. The company's patent estate includes a novel class of surfactants invented by P2's chief scientist, and licensed from Yale.
Retail Optimization, Inc. Retail Optimization, Inc. is an emerging leader in space optimization software for retail stores. ROI's products are substantially more sophisticated than other products on the market, allowing space planning of a store to be done on a whole store basis, as opposed to the category by category basis that has been the current industry standard.
Iconic Therapeutics Iconic Therapeutics is developing hI-con1, a fusion protein therapeutic invented at Yale by Drs. Alan Garen and Zhiwei Hu. While hI-con1 may have utility against cancer (solid tumors) and other diseases, development has been focused on its utility in treating the wet form of age-related macular degeneration ("wet AMD"), the leading cause of blindness in the elderly. Wet AMD is characterized by the invasion of pathological blood vessels into the eye, which, together with the fluid they leak, obscure vision.

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